Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.000427	uM	7885.016	0.9927	0.9796	0.7137
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.00213	uM	7885.016	0.9436	0.8436	0.7137
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.0107	uM	7885.016	1.0209	1.0588	0.7137
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.0533	uM	7885.016	0.9355	0.8216	0.7137
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.267	uM	7885.016	0.9157	0.7677	0.7137
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	1.33	uM	7885.016	0.7201	0.2625	0.7137
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	6.67	uM	7885.016	0.2166	-0.7655	0.7137
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	33.3	uM	7885.016	0.6737	0.1500	0.7137
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	167	uM	7885.016	0.5830	-0.0609	0.7137
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.000427	uM	7886.016	0.9366	0.8259	0.7194
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.00213	uM	7886.016	0.9544	0.8743	0.7194
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.0107	uM	7886.016	0.9804	0.9456	0.7194
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.0533	uM	7886.016	1.0028	1.0078	0.7194
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	0.267	uM	7886.016	0.8305	0.5450	0.7194
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	1.33	uM	7886.016	0.5850	-0.0507	0.7194
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	6.67	uM	7886.016	0.2177	-0.7598	0.7194
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	33.3	uM	7886.016	0.2391	-0.7264	0.7194
MDA-MB-175-VII	HR+	Luminal	AG1478	EGFR	ErbB	167	uM	7886.016	0.2270	-0.7454	0.7194
MDA-MB-231	TNBC	Basal B	AG1478	EGFR	ErbB	0.000427	uM	7892.016	0.9977	0.9981	2.3475
MDA-MB-231	TNBC	Basal B	AG1478	EGFR	ErbB	0.00213	uM	7892.016	1.0499	1.0420	2.3475
MDA-MB-231	TNBC	Basal B	AG1478	EGFR	ErbB	0.0107	uM	7892.016	0.9527	0.9592	2.3475
MDA-MB-231	TNBC	Basal B	AG1478	EGFR	ErbB	0.0533	uM	7892.016	1.0438	1.0369	2.3475
MDA-MB-231	TNBC	Basal B	AG1478	EGFR	ErbB	0.267	uM	7892.016	1.0053	1.0045	2.3475
MDA-MB-231	TNBC	Basal B	AG1478	EGFR	ErbB	1.33	uM	7892.016	1.0605	1.0507	2.3475
MDA-MB-231	TNBC	Basal B	AG1478	EGFR	ErbB	6.67	uM	7892.016	0.9671	0.9717	2.3475

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)