Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7864.017 | 0.0893 | -0.5350 | 1.6561 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7865.017 | 0.9180 | 0.9126 | 1.9138 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7865.017 | 0.7761 | 0.7519 | 1.9138 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7865.017 | 0.8698 | 0.8595 | 1.9138 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7865.017 | 0.5881 | 0.5155 | 1.9138 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7865.017 | 0.4847 | 0.3699 | 1.9138 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7865.017 | 0.1431 | -0.2759 | 1.9138 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7865.017 | 0.0406 | -0.6248 | 1.9138 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7865.017 | 0.0421 | -0.6181 | 1.9138 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7865.017 | 0.0552 | -0.5597 | 1.9138 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9536.017 | 1.0024 | 1.0032 | 1.4526 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9536.017 | 1.0191 | 1.0262 | 1.4526 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9536.017 | 0.9672 | 0.9547 | 1.4526 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 9536.017 | 0.8118 | 0.7326 | 1.4526 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9536.017 | 0.7402 | 0.6258 | 1.4526 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9536.017 | 0.6413 | 0.4731 | 1.4526 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9536.017 | 0.3388 | -0.0505 | 1.4526 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9536.017 | 0.0698 | -0.6799 | 1.4526 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 9536.017 | 0.0671 | -0.6885 | 1.4526 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 10264.131 | 0.9901 | 0.9864 | 1.4548 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 10264.131 | 1.0296 | 1.0405 | 1.4548 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 10264.131 | 0.9788 | 0.9707 | 1.4548 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 10264.131 | 0.7971 | 0.7114 | 1.4548 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 10264.131 | 0.6458 | 0.4807 | 1.4548 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 10264.131 | 0.5818 | 0.3784 | 1.4548 |