Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7862.017 | 0.8748 | 0.8073 | 1.3198 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7862.017 | 0.9354 | 0.9013 | 1.3198 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7862.017 | 0.9250 | 0.8852 | 1.3198 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7862.017 | 0.5652 | 0.2981 | 1.3198 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7862.017 | 0.2421 | -0.3171 | 1.3198 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7862.017 | 0.1370 | -0.5565 | 1.3198 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7862.017 | 0.1323 | -0.5679 | 1.3198 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7862.017 | 0.1127 | -0.6175 | 1.3198 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7863.017 | 1.0482 | 1.0487 | 1.9568 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7863.017 | 1.0277 | 1.0282 | 1.9568 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7863.017 | 0.9911 | 0.9909 | 1.9568 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7863.017 | 0.8431 | 0.8329 | 1.9568 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7863.017 | 0.6497 | 0.6044 | 1.9568 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7863.017 | 0.4610 | 0.3463 | 1.9568 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7863.017 | 0.1457 | -0.2528 | 1.9568 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7863.017 | 0.0914 | -0.4110 | 1.9568 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7863.017 | 0.0969 | -0.3933 | 1.9568 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7864.017 | 1.0177 | 1.0213 | 1.6561 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7864.017 | 0.9558 | 0.9462 | 1.6561 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7864.017 | 0.9797 | 0.9754 | 1.6561 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7864.017 | 0.8951 | 0.8705 | 1.6561 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7864.017 | 0.6483 | 0.5395 | 1.6561 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7864.017 | 0.5208 | 0.3488 | 1.6561 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7864.017 | 0.1548 | -0.3516 | 1.6561 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7864.017 | 0.0824 | -0.5570 | 1.6561 |