Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 9501.03 | 0.9290 | 0.7977 | 0.6902 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 9501.03 | 0.9109 | 0.7471 | 0.6902 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 9501.03 | 0.7715 | 0.3733 | 0.6902 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 9501.03 | 0.1627 | -0.8560 | 0.6902 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 9501.03 | 0.0207 | -0.9928 | 0.6902 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 9501.03 | 0.0122 | -0.9966 | 0.6902 | |
| HMT-3522 S1 | Unknown | Unknown | 5-FU | TYMS | TYMS | 0.0492 | uM | 7911.017 | 1.0677 | 1.0828 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | 5-FU | TYMS | TYMS | 0.246 | uM | 7911.017 | 1.0374 | 1.0460 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | 5-FU | TYMS | TYMS | 1.23 | uM | 7911.017 | 0.9279 | 0.9095 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | 5-FU | TYMS | TYMS | 6.15 | uM | 7911.017 | 0.8131 | 0.7595 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | 5-FU | TYMS | TYMS | 30.7 | uM | 7911.017 | 0.8009 | 0.7432 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | 5-FU | TYMS | TYMS | 154 | uM | 7911.017 | 0.7262 | 0.6406 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | 5-FU | TYMS | TYMS | 769 | uM | 7911.017 | 0.4073 | 0.1468 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | 5-FU | TYMS | TYMS | 3840 | uM | 7911.017 | 0.2100 | -0.2389 | 1.6151 | |
| HMT-3522 S1 | Unknown | Unknown | 5-FU | TYMS | TYMS | 19200 | uM | 7911.017 | 0.1408 | -0.4058 | 1.6151 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7861.017 | 0.9422 | 0.9352 | 1.8068 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7861.017 | 0.9956 | 0.9951 | 1.8068 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7861.017 | 0.9257 | 0.9164 | 1.8068 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7861.017 | 0.9495 | 0.9434 | 1.8068 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7861.017 | 0.8037 | 0.7721 | 1.8068 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7861.017 | 0.6492 | 0.5747 | 1.8068 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7861.017 | 0.4566 | 0.2960 | 1.8068 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7861.017 | 0.2532 | -0.0648 | 1.8068 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7861.017 | 0.1347 | -0.3407 | 1.8068 | |
| Hs 578T | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7862.017 | 0.9649 | 0.9466 | 1.3198 |