Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7821.017 | 1.0461 | 1.2523 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7821.017 | 1.0293 | 1.1584 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7821.017 | 1.0814 | 1.4586 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7821.017 | 1.0249 | 1.1338 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7821.017 | 0.9250 | 0.6284 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7821.017 | 0.7208 | -0.1564 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7821.017 | 0.4714 | -0.7248 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7821.017 | 0.3248 | -0.8970 | 0.3792 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9278.017 | 1.0452 | 1.1688 | 0.5453 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9278.017 | 1.0149 | 1.0551 | 0.5453 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9278.017 | 0.9883 | 0.9573 | 0.5453 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 9278.017 | 0.9502 | 0.8210 | 0.5453 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9278.017 | 0.9779 | 0.9195 | 0.5453 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9278.017 | 0.9028 | 0.6580 | 0.5453 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9278.017 | 0.5715 | -0.2832 | 0.5453 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9278.017 | 0.3990 | -0.6291 | 0.5453 | |
| HCC1419 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 9278.017 | 0.2659 | -0.8238 | 0.5453 | |
| HCC1428 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9294.017 | 0.8012 | 0.5242 | 0.8160 | |
| HCC1428 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9294.017 | 0.7921 | 0.5031 | 0.8160 | |
| HCC1428 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9294.017 | 0.9782 | 0.9466 | 0.8160 | |
| HCC1428 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 9294.017 | 0.8252 | 0.5804 | 0.8160 | |
| HCC1428 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9294.017 | 0.4793 | -0.1879 | 0.8160 | |
| HCC1428 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9294.017 | 0.2510 | -0.6324 | 0.8160 | |
| HCC1428 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9294.017 | 0.1884 | -0.7414 | 0.8160 | |
| HCC1428 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9294.017 | 0.1587 | -0.7904 | 0.8160 |