Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7837.016 | 0.4155 | 0.2300 | 1.8067 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7839.016 | 1.1775 | 1.2215 | 1.5556 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7839.016 | 0.8585 | 0.8131 | 1.5556 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7839.016 | 1.1763 | 1.2201 | 1.5556 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7839.016 | 0.8654 | 0.8226 | 1.5556 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7839.016 | 0.9241 | 0.9011 | 1.5556 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7839.016 | 0.5821 | 0.4124 | 1.5556 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7839.016 | 0.5479 | 0.3584 | 1.5556 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7839.016 | 0.5827 | 0.4133 | 1.5556 | |
| HCC1954 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7839.016 | 0.3137 | -0.0508 | 1.5556 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7840.016 | 0.9401 | 0.7638 | 0.4918 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7840.016 | 1.0153 | 1.0626 | 0.4918 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7840.016 | 0.9489 | 0.7976 | 0.4918 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7840.016 | 0.8858 | 0.5629 | 0.4918 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7840.016 | 0.9203 | 0.6892 | 0.4918 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7840.016 | 0.8180 | 0.3295 | 0.4918 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7840.016 | 0.7161 | 0.0142 | 0.4918 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7840.016 | 0.3126 | -0.8120 | 0.4918 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7840.016 | 0.5613 | -0.3818 | 0.4918 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7841.016 | 0.9277 | 0.6922 | 0.4493 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7841.016 | 1.0482 | 1.2208 | 0.4493 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7841.016 | 1.0559 | 1.2573 | 0.4493 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7841.016 | 0.9452 | 0.7640 | 0.4493 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7841.016 | 0.9703 | 0.8703 | 0.4493 | |
| HCC202 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7841.016 | 0.8808 | 0.5076 | 0.4493 |