Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MCF 10F
NM
-
AG1478
EGFR
ErbB
6.67
uM
7872.016
0.4156 0.1065 1.4834
MCF 10F
NM
-
AG1478
EGFR
ErbB
33.3
uM
7872.016
0.4050 0.0875 1.4834
MCF 10F
NM
-
AG1478
EGFR
ErbB
167
uM
7872.016
0.2917 -0.1284 1.4834
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.000427
uM
7491.016
0.9927 0.9781 0.6625
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.00213
uM
7491.016
0.9478 0.8446 0.6625
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.0107
uM
7491.016
0.9601 0.8807 0.6625
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.0533
uM
7491.016
0.8539 0.5757 0.6625
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.267
uM
7491.016
0.5912 -0.0955 0.6625
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
1.33
uM
7491.016
0.3012 -0.6731 0.6625
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
6.67
uM
7491.016
0.3032 -0.6698 0.6625
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
33.3
uM
7491.016
0.1906 -0.8362 0.6625
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
167
uM
7491.016
0.1533 -0.8820 0.6625
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.000427
uM
7873.016
0.9698 0.9717 2.1516
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.00213
uM
7873.016
0.9573 0.9599 2.1516
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.0107
uM
7873.016
0.9899 0.9906 2.1516
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.0533
uM
7873.016
1.0337 1.0310 2.1516
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
0.267
uM
7873.016
0.9533 0.9560 2.1516
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
1.33
uM
7873.016
0.3681 0.2569 2.1516
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
6.67
uM
7873.016
0.2579 0.0653 2.1516
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
33.3
uM
7873.016
0.4513 0.3818 2.1516
MCF12A
NM
Basal B
AG1478
EGFR
ErbB
167
uM
7873.016
0.2682 0.0848 2.1516
MCF7
HR+
Luminal
AG1478
EGFR
ErbB
0.000427
uM
7874.016
0.8695 0.8321 1.5947
MCF7
HR+
Luminal
AG1478
EGFR
ErbB
0.00213
uM
7874.016
0.9696 0.9616 1.5947
MCF7
HR+
Luminal
AG1478
EGFR
ErbB
0.0107
uM
7874.016
0.9708 0.9632 1.5947
MCF7
HR+
Luminal
AG1478
EGFR
ErbB
0.0533
uM
7874.016
0.9799 0.9747 1.5947