Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 5910.074 | 0.0005 | -0.8162 | 3.2172 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14723.203 | 0.9859 | 0.9842 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14723.203 | 0.9859 | 0.9842 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14723.203 | 0.8645 | 0.8437 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14723.203 | 0.8645 | 0.8437 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14723.203 | 0.6971 | 0.6348 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14723.203 | 0.6971 | 0.6348 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14723.203 | 0.0154 | -0.8057 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14723.203 | 0.0154 | -0.8057 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14723.203 | 0.0172 | -0.7931 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14723.203 | 0.0172 | -0.7931 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14723.203 | 0.0113 | -0.8364 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14723.203 | 0.0113 | -0.8364 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14723.203 | 0.0106 | -0.8426 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14723.203 | 0.0106 | -0.8426 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14723.203 | 0.0108 | -0.8408 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14723.203 | 0.0108 | -0.8408 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14723.203 | 0.0119 | -0.8314 | 1.7902 | |
| BT-549 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14723.203 | 0.0119 | -0.8314 | 1.7902 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15272.203 | 1.0119 | 1.0123 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15272.203 | 1.0119 | 1.0123 | 1.9412 |