Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9402.037 | 0.4892 | -0.7009 | 0.3763 | |
| HCC202 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9402.037 | 0.3054 | -0.9145 | 0.3763 | |
| HCC202 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9402.037 | 0.0159 | -1.0000 | 0.3763 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7845.05 | 0.9321 | 0.7248 | 0.4747 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7845.05 | 0.9453 | 0.7764 | 0.4747 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7845.05 | 0.9166 | 0.6648 | 0.4747 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7845.05 | 0.9934 | 0.9721 | 0.4747 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7845.05 | 0.5412 | -0.4513 | 0.4747 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7845.05 | 0.4044 | -0.7030 | 0.4747 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7845.05 | 0.3692 | -0.7548 | 0.4747 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7845.05 | 0.3308 | -0.8054 | 0.4747 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7845.05 | 0.1330 | -0.9714 | 0.4747 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7846.05 | 0.9576 | 0.7861 | 0.3833 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7846.05 | 0.9467 | 0.7338 | 0.3833 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7846.05 | 0.9682 | 0.8380 | 0.3833 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7846.05 | 0.9834 | 0.9145 | 0.3833 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7846.05 | 0.6008 | -0.4706 | 0.3833 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7846.05 | 0.3611 | -0.8597 | 0.3833 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7846.05 | 0.3439 | -0.8765 | 0.3833 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7846.05 | 0.3191 | -0.8984 | 0.3833 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7846.05 | 0.3274 | -0.8914 | 0.3833 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7848.037 | 0.9764 | 0.9051 | 0.4916 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7848.037 | 1.0594 | 1.2491 | 0.4916 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7848.037 | 1.0234 | 1.0965 | 0.4916 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7848.037 | 1.0546 | 1.2286 | 0.4916 |