Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 9797.006 | 0.9398 | 0.7250 | 0.4196 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 9797.006 | 0.1155 | -0.9883 | 0.4196 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 9797.006 | 0.0072 | -1.0000 | 0.4196 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10139.034 | 1.0060 | 1.0144 | 0.8381 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 10139.034 | 0.9928 | 0.9828 | 0.8381 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 10139.034 | 1.0135 | 1.0322 | 0.8381 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 10139.034 | 0.9484 | 0.8774 | 0.8381 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 10139.034 | 0.9354 | 0.8468 | 0.8381 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 10139.034 | 0.9203 | 0.8112 | 0.8381 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 10139.034 | 0.9034 | 0.7716 | 0.8381 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 10139.034 | 0.8168 | 0.5709 | 0.8381 | ||
| SUM1315MO2 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 10139.034 | 0.0495 | -0.9445 | 0.8381 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7917.018 | 1.0561 | 1.0386 | 2.8573 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7917.018 | 0.9725 | 0.9806 | 2.8573 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7917.018 | 0.9498 | 0.9643 | 2.8573 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7917.018 | 0.6647 | 0.7337 | 2.8573 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7917.018 | 0.6619 | 0.7310 | 2.8573 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7917.018 | 0.6476 | 0.7179 | 2.8573 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 7917.018 | 0.4429 | 0.5040 | 2.8573 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 7917.018 | 0.2010 | 0.1406 | 2.8573 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 7917.018 | 0.0096 | -0.6063 | 2.8573 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9830.006 | 1.0941 | 1.1076 | 1.7160 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 9830.006 | 1.0398 | 1.0460 | 1.7160 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 9830.006 | 0.9509 | 0.9421 | 1.7160 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 9830.006 | 0.6398 | 0.5417 | 1.7160 |