Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 9830.006 | 0.6616 | 0.5721 | 1.7160 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 9830.006 | 0.6533 | 0.5606 | 1.7160 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 9830.006 | 0.6122 | 0.5025 | 1.7160 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 9830.006 | 0.2577 | -0.0925 | 1.7160 | ||
| SUM149PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 9830.006 | 0.0040 | -0.9195 | 1.7160 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7918.018 | 1.0583 | 1.0379 | 3.0213 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7918.018 | 1.0324 | 1.0212 | 3.0213 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7918.018 | 0.9793 | 0.9862 | 3.0213 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7918.018 | 0.7376 | 0.8084 | 3.0213 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7918.018 | 0.7053 | 0.7818 | 3.0213 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7918.018 | 0.6581 | 0.7414 | 3.0213 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 7918.018 | 0.3840 | 0.4570 | 3.0213 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 7918.018 | 0.0539 | -0.2395 | 3.0213 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 7918.018 | 0.0094 | -0.5727 | 3.0213 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7920.018 | 1.0130 | 1.0059 | 4.3723 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7920.018 | 1.0938 | 1.0414 | 4.3723 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7920.018 | 0.9582 | 0.9805 | 4.3723 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7920.018 | 0.7797 | 0.8894 | 4.3723 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7920.018 | 0.7154 | 0.8525 | 4.3723 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7920.018 | 0.7042 | 0.8459 | 4.3723 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 7920.018 | 0.4722 | 0.6846 | 4.3723 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 7920.018 | 0.5166 | 0.7196 | 4.3723 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 7920.018 | 0.0092 | -0.3159 | 4.3723 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9042.018 | 0.8565 | 0.9069 | 3.2484 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 9042.018 | 0.9101 | 0.9428 | 3.2484 |