Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 9042.018 | 0.8797 | 0.9226 | 3.2484 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 9042.018 | 0.6234 | 0.7292 | 3.2484 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 9042.018 | 0.5588 | 0.6720 | 3.2484 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 9042.018 | 0.5796 | 0.6909 | 3.2484 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 9042.018 | 0.4956 | 0.6113 | 3.2484 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 9042.018 | 0.4637 | 0.5787 | 3.2484 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 9042.018 | 0.0008 | -0.7773 | 3.2484 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9844.034 | 1.1006 | 1.0877 | 2.2318 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 9844.034 | 1.0257 | 1.0229 | 2.2318 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 9844.034 | 1.0003 | 1.0003 | 2.2318 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 9844.034 | 0.6969 | 0.7012 | 2.2318 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 9844.034 | 0.7400 | 0.7476 | 2.2318 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 9844.034 | 0.6428 | 0.6407 | 2.2318 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 9844.034 | 0.6621 | 0.6626 | 2.2318 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 9844.034 | 0.5224 | 0.4951 | 2.2318 | ||
| SUM159PT | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 9844.034 | 0.0258 | -0.6118 | 2.2318 | ||
| SUM185PE | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.00128 | uM | 10146.124 | 1.0693 | 1.1495 | 0.9296 | ||
| SUM185PE | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.0064 | uM | 10146.124 | 1.1082 | 1.2337 | 0.9296 | ||
| SUM185PE | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.032 | uM | 10146.124 | 1.1297 | 1.2804 | 0.9296 | ||
| SUM185PE | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.16 | uM | 10146.124 | 0.9474 | 0.8871 | 0.9296 | ||
| SUM185PE | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.8 | uM | 10146.124 | 0.8797 | 0.7425 | 0.9296 | ||
| SUM185PE | TNBC | Luminal | CGC-11047 | Polyamine analogue | 4 | uM | 10146.124 | 0.8391 | 0.6560 | 0.9296 | ||
| SUM185PE | TNBC | Luminal | CGC-11047 | Polyamine analogue | 20 | uM | 10146.124 | 0.9337 | 0.8577 | 0.9296 | ||
| SUM185PE | TNBC | Luminal | CGC-11047 | Polyamine analogue | 100 | uM | 10146.124 | 0.8145 | 0.6039 | 0.9296 | ||
| SUM185PE | TNBC | Luminal | CGC-11047 | Polyamine analogue | 500 | uM | 10146.124 | 0.7457 | 0.4587 | 0.9296 |