Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 6 | uM | 7465.065 | 0.9699 | 0.9498 | 1.2013 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 30 | uM | 7465.065 | 1.0109 | 1.0182 | 1.2013 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 150 | uM | 7465.065 | 0.7085 | 0.5013 | 1.2013 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 750 | uM | 7465.065 | 0.3188 | -0.2277 | 1.2013 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 3750 | uM | 7465.065 | 0.1593 | -0.5665 | 1.2013 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 18700 | uM | 7465.065 | 0.1325 | -0.6283 | 1.2013 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.048 | uM | 7466.065 | 0.9818 | 0.9557 | 0.8210 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.24 | uM | 7466.065 | 1.0009 | 1.0022 | 0.8210 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 1.2 | uM | 7466.065 | 0.9863 | 0.9668 | 0.8210 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 6 | uM | 7466.065 | 0.9712 | 0.9302 | 0.8210 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 30 | uM | 7466.065 | 0.9888 | 0.9726 | 0.8210 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 150 | uM | 7466.065 | 0.6851 | 0.2618 | 0.8210 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 750 | uM | 7466.065 | 0.3206 | -0.4996 | 0.8210 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 3750 | uM | 7466.065 | 0.1891 | -0.7370 | 0.8210 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 18700 | uM | 7466.065 | 0.1432 | -0.8125 | 0.8210 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.048 | uM | 7467.065 | 1.0183 | 1.0294 | 1.2393 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.24 | uM | 7467.065 | 1.0628 | 1.1008 | 1.2393 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 1.2 | uM | 7467.065 | 1.0221 | 1.0355 | 1.2393 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 6 | uM | 7467.065 | 1.0672 | 1.1077 | 1.2393 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 30 | uM | 7467.065 | 1.0297 | 1.0478 | 1.2393 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 150 | uM | 7467.065 | 0.7089 | 0.5152 | 1.2393 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 750 | uM | 7467.065 | 0.2557 | -0.3345 | 1.2393 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 3750 | uM | 7467.065 | 0.1053 | -0.6747 | 1.2393 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 18700 | uM | 7467.065 | 0.0782 | -0.7441 | 1.2393 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 7468.065 | 0.9317 | 0.9092 | 1.5219 |