Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 150 | uM | 7462.065 | 0.4934 | -0.6655 | 0.3950 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 750 | uM | 7462.065 | 0.0253 | -0.9998 | 0.3950 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 3750 | uM | 7462.065 | 0.0132 | -1.0000 | 0.3950 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 18700 | uM | 7462.065 | 0.0101 | -1.0000 | 0.3950 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 0.048 | uM | 7463.065 | 0.9417 | 0.7829 | 0.5226 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 0.24 | uM | 7463.065 | 0.9380 | 0.7693 | 0.5226 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 1.2 | uM | 7463.065 | 0.9483 | 0.8067 | 0.5226 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 6 | uM | 7463.065 | 0.9491 | 0.8096 | 0.5226 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 30 | uM | 7463.065 | 0.9104 | 0.6711 | 0.5226 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 150 | uM | 7463.065 | 0.5162 | -0.4356 | 0.5226 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 750 | uM | 7463.065 | 0.0188 | -0.9990 | 0.5226 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 3750 | uM | 7463.065 | 0.0065 | -0.9999 | 0.5226 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 18700 | uM | 7463.065 | 0.0069 | -0.9999 | 0.5226 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 0.048 | uM | 7464.065 | 0.9986 | 0.9961 | 0.7107 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 0.24 | uM | 7464.065 | 0.9743 | 0.9282 | 0.7107 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 1.2 | uM | 7464.065 | 1.0264 | 1.0747 | 0.7107 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 6 | uM | 7464.065 | 0.9792 | 0.9417 | 0.7107 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 30 | uM | 7464.065 | 0.9538 | 0.8713 | 0.7107 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 150 | uM | 7464.065 | 0.5790 | -0.0730 | 0.7107 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 750 | uM | 7464.065 | 0.0398 | -0.9786 | 0.7107 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 3750 | uM | 7464.065 | 0.0140 | -0.9951 | 0.7107 | |
| HCC2185 | TNBC | Luminal | Vorinostat | HDAC | HDAC | 18700 | uM | 7464.065 | 0.0124 | -0.9959 | 0.7107 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.048 | uM | 7465.065 | 0.9831 | 0.9717 | 1.2013 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.24 | uM | 7465.065 | 0.9229 | 0.8707 | 1.2013 | |
| HCC3153 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 1.2 | uM | 7465.065 | 0.9286 | 0.8804 | 1.2013 |