Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 7468.065 | 0.9561 | 0.9419 | 1.5219 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 7468.065 | 0.9814 | 0.9755 | 1.5219 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7468.065 | 0.8988 | 0.8645 | 1.5219 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 7468.065 | 0.7108 | 0.5981 | 1.5219 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 7468.065 | 0.1277 | -0.4827 | 1.5219 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 7468.065 | 0.0154 | -0.8710 | 1.5219 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7468.065 | 0.0154 | -0.8710 | 1.5219 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 7468.065 | 0.0181 | -0.8566 | 1.5219 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 7469.065 | 1.0065 | 1.0065 | 2.0006 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 7469.065 | 1.0181 | 1.0180 | 2.0006 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 7469.065 | 0.9726 | 0.9724 | 2.0006 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7469.065 | 0.9881 | 0.9881 | 2.0006 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 7469.065 | 0.7702 | 0.7553 | 2.0006 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 7469.065 | 0.2062 | -0.0916 | 2.0006 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 7469.065 | 0.0313 | -0.6460 | 2.0006 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7469.065 | 0.0295 | -0.6563 | 2.0006 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 18700 | uM | 7469.065 | 0.0283 | -0.6634 | 2.0006 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 10418.065 | 0.8939 | 0.7751 | 0.9401 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 10418.065 | 0.8905 | 0.7679 | 0.9401 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 10418.065 | 0.8537 | 0.6902 | 0.9401 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 10418.065 | 0.8846 | 0.7553 | 0.9401 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 10418.065 | 0.5950 | 0.1513 | 0.9401 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 10418.065 | 0.1310 | -0.7698 | 0.9401 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 10418.065 | 0.0324 | -0.9480 | 0.9401 | |
| HCC38 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 10418.065 | 0.0286 | -0.9543 | 0.9401 |