Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7820.042 | 0.0163 | -0.9993 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7821.042 | 0.9094 | 0.6839 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7821.042 | 0.9602 | 0.8583 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7821.042 | 0.9631 | 0.8683 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7821.042 | 0.8010 | 0.3383 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7821.042 | 0.7107 | 0.0775 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7821.042 | 0.6994 | 0.0466 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7821.042 | 0.6814 | -0.0017 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7821.042 | 0.5358 | -0.3539 | 0.5522 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7821.042 | 0.0204 | -0.9983 | 0.5522 | |
| HCC1428 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000822 | uM | 9294.125 | 0.9743 | 0.9270 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00411 | uM | 9294.125 | 0.8489 | 0.5827 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0205 | uM | 9294.125 | 0.8309 | 0.5349 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.103 | uM | 9294.125 | 0.8105 | 0.4812 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.514 | uM | 9294.125 | 0.8607 | 0.6141 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 2.57 | uM | 9294.125 | 0.7999 | 0.4537 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 12.8 | uM | 9294.125 | 0.4700 | -0.3199 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 64.2 | uM | 9294.125 | 0.0163 | -0.9944 | 0.6999 | |
| HCC1428 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 321 | uM | 9294.125 | 0.0110 | -0.9968 | 0.6999 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7824.018 | 1.0933 | 1.1407 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7824.018 | 1.1772 | 1.2649 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7824.018 | 1.1330 | 1.1997 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7824.018 | 1.0991 | 1.1494 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7824.018 | 0.7560 | 0.6159 | 1.3115 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7824.018 | 0.6150 | 0.3806 | 1.3115 |