Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7816.042 | 0.9996 | 0.9991 | 0.9332 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7816.042 | 0.9871 | 0.9723 | 0.9332 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7816.042 | 0.3363 | -0.3779 | 0.9332 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7816.042 | 0.2060 | -0.6320 | 0.9332 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7816.042 | 0.1864 | -0.6695 | 0.9332 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7816.042 | 0.1751 | -0.6908 | 0.9332 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7816.042 | 0.1588 | -0.7217 | 0.9332 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7816.042 | 0.0177 | -0.9736 | 0.9332 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7818.018 | 0.9332 | 0.8655 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7818.018 | 0.9313 | 0.8617 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7818.018 | 0.8996 | 0.7978 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7818.018 | 0.8956 | 0.7897 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7818.018 | 0.7657 | 0.5285 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7818.018 | 0.6967 | 0.3898 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7818.018 | 0.7270 | 0.4506 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7818.018 | 0.5805 | 0.1564 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7818.018 | 0.0179 | -0.9652 | 0.9928 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7820.042 | 0.9737 | 0.9002 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7820.042 | 0.8849 | 0.5821 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7820.042 | 0.8967 | 0.6226 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7820.042 | 0.8051 | 0.3198 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7820.042 | 0.8095 | 0.3336 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7820.042 | 0.7141 | 0.0487 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7820.042 | 0.7154 | 0.0524 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7820.042 | 0.5850 | -0.2846 | 0.5216 |