Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7812.042 | 0.9917 | 0.9830 | 0.9722 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7812.042 | 0.0887 | -0.8345 | 0.9722 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7812.042 | 0.1665 | -0.6836 | 0.9722 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7812.042 | 0.1954 | -0.6271 | 0.9722 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7812.042 | 0.2610 | -0.4977 | 0.9722 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7812.042 | 0.0123 | -0.9783 | 0.9722 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7813.018 | 0.9332 | 0.8423 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7813.018 | 0.6018 | 0.0941 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7813.018 | 0.3203 | -0.4827 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7813.018 | 0.3291 | -0.4658 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7813.018 | 0.1880 | -0.7253 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7813.018 | 0.2109 | -0.6850 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7813.018 | 0.0709 | -0.9138 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7813.018 | 0.0020 | -0.9987 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7813.018 | 0.0051 | -0.9963 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7814.042 | 0.9936 | 0.9847 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7814.042 | 0.8902 | 0.7418 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7814.042 | 0.8326 | 0.6087 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7814.042 | 0.2533 | -0.6090 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7814.042 | 0.2192 | -0.6707 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7814.042 | 0.1551 | -0.7817 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7814.042 | 0.1370 | -0.8116 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7814.042 | 0.1310 | -0.8215 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7814.042 | 0.0119 | -0.9897 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7816.042 | 0.9377 | 0.8668 | 0.9332 |