Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7809.018 | 0.5260 | 0.3626 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7809.018 | 0.5902 | 0.4597 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7809.018 | 0.4778 | 0.2866 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7809.018 | 0.5648 | 0.4218 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00119 | uM | 7810.006 | 1.0659 | 1.1355 | 0.9730 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00593 | uM | 7810.006 | 0.8265 | 0.6442 | 0.9730 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0297 | uM | 7810.006 | 0.9877 | 0.9747 | 0.9730 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.148 | uM | 7810.006 | 0.8774 | 0.7484 | 0.9730 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.742 | uM | 7810.006 | 0.4795 | -0.0604 | 0.9730 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 3.71 | uM | 7810.006 | 0.5076 | -0.0037 | 0.9730 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 18.5 | uM | 7810.006 | 0.5611 | 0.1044 | 0.9730 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 92.7 | uM | 7810.006 | 0.5600 | 0.1021 | 0.9730 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 463 | uM | 7810.006 | 0.1096 | -0.7939 | 0.9730 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7811.018 | 0.9983 | 0.9927 | 0.4694 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7811.018 | 0.9967 | 0.9858 | 0.4694 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7811.018 | 1.0241 | 1.1043 | 0.4694 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7811.018 | 0.6490 | -0.2039 | 0.4694 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7811.018 | 0.0825 | -0.9902 | 0.4694 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7811.018 | 0.1305 | -0.9739 | 0.4694 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7811.018 | 0.1800 | -0.9482 | 0.4694 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7811.018 | 0.2759 | -0.8713 | 0.4694 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7811.018 | 0.0421 | -0.9977 | 0.4694 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7812.042 | 1.1103 | 1.2273 | 0.9722 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7812.042 | 1.0035 | 1.0072 | 0.9722 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7812.042 | 0.8078 | 0.6058 | 0.9722 |