Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14233.189 | 0.4712 | -0.7267 | 0.3780 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14233.189 | 0.1901 | -0.9752 | 0.3780 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14233.189 | 0.1465 | -0.9876 | 0.3780 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14122.189 | 1.0185 | 1.0122 | 3.0232 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14122.189 | 0.9444 | 0.9625 | 3.0232 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14122.189 | 0.9685 | 0.9789 | 3.0232 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14122.189 | 1.0044 | 1.0029 | 3.0232 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14122.189 | 1.0122 | 1.0081 | 3.0232 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14122.189 | 0.1687 | 0.1101 | 3.0232 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14122.189 | 0.0006 | -0.8306 | 3.0232 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14122.189 | 0.0044 | -0.6678 | 3.0232 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14122.189 | 0.0024 | -0.7285 | 3.0232 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14152.189 | 1.0207 | 1.0187 | 2.1948 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14152.189 | 0.9623 | 0.9653 | 2.1948 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14152.189 | 1.0133 | 1.0121 | 2.1948 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14152.189 | 0.9169 | 0.9225 | 2.1948 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14152.189 | 0.9337 | 0.9385 | 2.1948 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14152.189 | 0.3407 | 0.2246 | 2.1948 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14152.189 | 0.0015 | -0.8980 | 2.1948 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14152.189 | 0.0103 | -0.7514 | 2.1948 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14152.189 | 0.0086 | -0.7707 | 2.1948 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14200.189 | 0.9960 | 0.9976 | 3.2969 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14200.189 | 0.9871 | 0.9921 | 3.2969 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14200.189 | 1.0400 | 1.0239 | 3.2969 | |
| BT-549 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14200.189 | 1.0002 | 1.0001 | 3.2969 |