Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7867.016 | 1.1619 | 1.1369 | 2.2657 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7867.016 | 1.0654 | 1.0567 | 2.2657 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7867.016 | 0.8790 | 0.8893 | 2.2657 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7867.016 | 0.5572 | 0.5450 | 2.2657 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7867.016 | 0.1517 | -0.1299 | 2.2657 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7867.016 | 0.1625 | -0.1032 | 2.2657 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7867.016 | 0.1580 | -0.1143 | 2.2657 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7867.016 | 0.1490 | -0.1368 | 2.2657 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7868.016 | 0.8800 | 0.8818 | 2.0998 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7868.016 | 1.0376 | 1.0355 | 2.0998 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7868.016 | 0.9504 | 0.9522 | 2.0998 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7868.016 | 0.9873 | 0.9879 | 2.0998 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7868.016 | 0.4688 | 0.3942 | 2.0998 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7868.016 | 0.1490 | -0.1922 | 2.0998 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7868.016 | 0.1517 | -0.1853 | 2.0998 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7868.016 | 0.0523 | -0.5096 | 2.0998 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7868.016 | 0.0065 | -0.8186 | 2.0998 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7870.016 | 1.0174 | 1.0165 | 2.1045 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7870.016 | 1.0191 | 1.0181 | 2.1045 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7870.016 | 1.0255 | 1.0241 | 2.1045 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7870.016 | 0.9467 | 0.9486 | 2.1045 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7870.016 | 0.5407 | 0.4933 | 2.1045 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7870.016 | 0.1640 | -0.1528 | 2.1045 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7870.016 | 0.1743 | -0.1280 | 2.1045 | |
MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7870.016 | 0.1755 | -0.1251 | 2.1045 |