Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7865.016 | 0.7615 | 0.7198 | 1.8047 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7865.016 | 1.0981 | 1.1064 | 1.8047 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7865.016 | 1.1837 | 1.1959 | 1.8047 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7865.016 | 1.2757 | 1.2889 | 1.8047 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7865.016 | 0.5667 | 0.4600 | 1.8047 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7865.016 | 0.8557 | 0.8345 | 1.8047 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 9536.019 | 1.0128 | 1.0164 | 1.5595 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 9536.019 | 0.9712 | 0.9628 | 1.5595 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 9536.019 | 0.9981 | 0.9975 | 1.5595 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 9536.019 | 1.0064 | 1.0083 | 1.5595 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 9536.019 | 1.0024 | 1.0031 | 1.5595 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 9536.019 | 1.0145 | 1.0185 | 1.5595 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 9536.019 | 0.9661 | 0.9563 | 1.5595 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 9536.019 | 1.0256 | 1.0327 | 1.5595 | |
| LY2 | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 9536.019 | 0.9115 | 0.8846 | 1.5595 | |
| MB 157 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.000427 | uM | 9039.016 | 0.9440 | 0.8001 | 0.5468 | |
| MB 157 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.00213 | uM | 9039.016 | 1.0497 | 1.1856 | 0.5468 | |
| MB 157 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.0107 | uM | 9039.016 | 0.9628 | 0.8660 | 0.5468 | |
| MB 157 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.0533 | uM | 9039.016 | 0.9221 | 0.7243 | 0.5468 | |
| MB 157 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.267 | uM | 9039.016 | 0.9116 | 0.6885 | 0.5468 | |
| MB 157 | Unknown | Unknown | AG1478 | EGFR | ErbB | 1.33 | uM | 9039.016 | 0.9132 | 0.6938 | 0.5468 | |
| MB 157 | Unknown | Unknown | AG1478 | EGFR | ErbB | 6.67 | uM | 9039.016 | 0.9106 | 0.6851 | 0.5468 | |
| MB 157 | Unknown | Unknown | AG1478 | EGFR | ErbB | 33.3 | uM | 9039.016 | 0.5312 | -0.3711 | 0.5468 | |
| MB 157 | Unknown | Unknown | AG1478 | EGFR | ErbB | 167 | uM | 9039.016 | 0.8173 | 0.3828 | 0.5468 | |
| MCF 10A | NM | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7867.016 | 0.9923 | 0.9932 | 2.2657 |