Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10872.152 | 0.9092 | 0.8839 | 1.5916 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10872.152 | 0.9705 | 0.9627 | 1.5916 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10872.152 | 0.9272 | 0.9073 | 1.5916 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10872.152 | 0.9931 | 0.9914 | 1.5916 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10872.152 | 0.8718 | 0.8349 | 1.5916 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10872.152 | 0.9041 | 0.8773 | 1.5916 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10872.152 | 0.1876 | -0.3011 | 1.5916 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10872.152 | 0.0082 | -0.9020 | 1.5916 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 10872.152 | 0.0083 | -0.9016 | 1.5916 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12523.152 | 1.0378 | 1.0900 | 0.8423 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12523.152 | 1.0224 | 1.0533 | 0.8423 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12523.152 | 1.0369 | 1.0879 | 0.8423 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12523.152 | 1.0151 | 1.0359 | 0.8423 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12523.152 | 1.0952 | 1.2281 | 0.8423 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12523.152 | 1.0603 | 1.1441 | 0.8423 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12523.152 | 0.4967 | -0.1286 | 0.8423 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12523.152 | 0.0115 | -0.9901 | 0.8423 | |
| HCC1569 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 12523.152 | 0.0107 | -0.9908 | 0.8423 | |
| HCC1806 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12239.152 | 0.8872 | 0.8945 | 2.2104 | |
| HCC1806 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12239.152 | 0.9361 | 0.9412 | 2.2104 | |
| HCC1806 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12239.152 | 0.9174 | 0.9235 | 2.2104 | |
| HCC1806 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12239.152 | 1.0502 | 1.0448 | 2.2104 | |
| HCC1806 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12239.152 | 0.9202 | 0.9262 | 2.2104 | |
| HCC1806 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12239.152 | 0.8115 | 0.8197 | 2.2104 | |
| HCC1806 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12239.152 | 0.0886 | -0.3319 | 2.2104 |