Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12001.159 | 1.0078 | 1.0221 | 0.7107 | |
| HCC1419 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12001.159 | 1.0070 | 1.0198 | 0.7107 | |
| HCC1419 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12001.159 | 0.8771 | 0.6631 | 0.7107 | |
| HCC1419 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12001.159 | 0.8730 | 0.6522 | 0.7107 | |
| HCC1419 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12001.159 | 0.3705 | -0.5053 | 0.7107 | |
| HCC1419 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12001.159 | 0.0115 | -0.9962 | 0.7107 | |
| HCC1419 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12001.159 | 0.0101 | -0.9969 | 0.7107 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10693.152 | 1.0517 | 1.1189 | 0.8734 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10693.152 | 0.9404 | 0.8642 | 0.8734 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10693.152 | 0.9947 | 0.9878 | 0.8734 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10693.152 | 0.9744 | 0.9414 | 0.8734 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10693.152 | 0.9930 | 0.9840 | 0.8734 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10693.152 | 0.9137 | 0.8037 | 0.8734 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10693.152 | 0.2837 | -0.5272 | 0.8734 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10693.152 | 0.0112 | -0.9883 | 0.8734 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10693.152 | 0.0114 | -0.9881 | 0.8734 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11936.159 | 0.9762 | 0.9365 | 0.7472 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11936.159 | 0.9679 | 0.9145 | 0.7472 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11936.159 | 0.9840 | 0.9574 | 0.7472 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11936.159 | 0.9951 | 0.9868 | 0.7472 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11936.159 | 0.9909 | 0.9757 | 0.7472 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11936.159 | 0.9951 | 0.9869 | 0.7472 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11936.159 | 0.3170 | -0.5702 | 0.7472 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11936.159 | 0.0142 | -0.9933 | 0.7472 | |
| HCC1428 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 11936.159 | 0.0134 | -0.9938 | 0.7472 |