Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12239.152 | 0.0099 | -0.7525 | 2.2104 | |
| HCC1806 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 12239.152 | 0.0081 | -0.7736 | 2.2104 | |
| HCC1937 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11849.159 | 0.9275 | 0.8830 | 1.2484 | |
| HCC1937 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11849.159 | 0.9289 | 0.8853 | 1.2484 | |
| HCC1937 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11849.159 | 0.9608 | 0.9370 | 1.2484 | |
| HCC1937 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11849.159 | 0.9164 | 0.8650 | 1.2484 | |
| HCC1937 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11849.159 | 0.8288 | 0.7207 | 1.2484 | |
| HCC1937 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11849.159 | 0.6130 | 0.3514 | 1.2484 | |
| HCC1937 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11849.159 | 0.0279 | -0.8863 | 1.2484 | |
| HCC1937 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11849.159 | 0.0088 | -0.9548 | 1.2484 | |
| HCC1937 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 11849.159 | 0.0059 | -0.9671 | 1.2484 | |
| HCC1954 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11055.152 | 1.0048 | 1.0058 | 1.6647 | |
| HCC1954 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11055.152 | 1.0449 | 1.0535 | 1.6647 | |
| HCC1954 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11055.152 | 1.0197 | 1.0236 | 1.6647 | |
| HCC1954 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11055.152 | 1.0916 | 1.1081 | 1.6647 | |
| HCC1954 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11055.152 | 0.9823 | 0.9786 | 1.6647 | |
| HCC1954 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11055.152 | 0.9393 | 0.9262 | 1.6647 | |
| HCC1954 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11055.152 | 0.6265 | 0.5102 | 1.6647 | |
| HCC1954 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11055.152 | 0.0168 | -0.8284 | 1.6647 | |
| HCC1954 | HER2amp | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 11055.152 | 0.0111 | -0.8660 | 1.6647 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10996.152 | 0.9808 | 0.9398 | 0.6343 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10996.152 | 0.9474 | 0.8368 | 0.6343 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10996.152 | 0.9669 | 0.8967 | 0.6343 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10996.152 | 0.9270 | 0.7748 | 0.6343 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10996.152 | 0.8980 | 0.6881 | 0.6343 |