Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7453.066 | 1.0388 | 1.0555 | 1.3901 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7453.066 | 0.9738 | 0.9621 | 1.3901 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7453.066 | 1.0099 | 1.0143 | 1.3901 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7453.066 | 1.0315 | 1.0451 | 1.3901 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7453.066 | 1.0203 | 1.0292 | 1.3901 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7453.066 | 0.9852 | 0.9787 | 1.3901 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7453.066 | 1.0718 | 1.1024 | 1.3901 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7453.066 | 0.9525 | 0.9312 | 1.3901 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7453.066 | 0.7383 | 0.6078 | 1.3901 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7454.066 | 0.8885 | 0.8228 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7454.066 | 0.7734 | 0.6348 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7454.066 | 0.8625 | 0.7809 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7454.066 | 0.9729 | 0.9573 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7454.066 | 0.8737 | 0.7991 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7454.066 | 0.8086 | 0.6929 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7454.066 | 0.8240 | 0.7182 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7454.066 | 0.8506 | 0.7616 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7454.066 | 0.8420 | 0.7476 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7455.066 | 1.0109 | 1.0168 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7455.066 | 0.8833 | 0.8175 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7455.066 | 0.9142 | 0.8664 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7455.066 | 0.9933 | 0.9897 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7455.066 | 0.9509 | 0.9238 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7455.066 | 0.9427 | 0.9112 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7455.066 | 1.0307 | 1.0472 | 1.2976 |