Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5905.066 | 1.0707 | 1.1871 | 0.7639 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5905.066 | 1.0111 | 1.0290 | 0.7639 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5905.066 | 1.0312 | 1.0822 | 0.7639 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 5905.066 | 1.0485 | 1.1280 | 0.7639 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 5905.066 | 1.0653 | 1.1728 | 0.7639 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 5905.066 | 1.0574 | 1.1517 | 0.7639 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 5905.066 | 0.9167 | 0.7848 | 0.7639 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5906.066 | 1.0019 | 1.0048 | 0.7892 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5906.066 | 1.0094 | 1.0238 | 0.7892 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5906.066 | 0.9760 | 0.9395 | 0.7892 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5906.066 | 1.0123 | 1.0313 | 0.7892 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5906.066 | 0.9765 | 0.9405 | 0.7892 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 5906.066 | 0.9724 | 0.9304 | 0.7892 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 5906.066 | 1.0334 | 1.0849 | 0.7892 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 5906.066 | 1.0191 | 1.0486 | 0.7892 | |
| BT-474 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 5906.066 | 0.8032 | 0.5150 | 0.7892 | |
| BT-483 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5908.066 | 0.9086 | 0.6199 | 0.4546 | |
| BT-483 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5908.066 | 0.9056 | 0.6080 | 0.4546 | |
| BT-483 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5908.066 | 0.9534 | 0.8008 | 0.4546 | |
| BT-483 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5908.066 | 0.9700 | 0.8702 | 0.4546 | |
| BT-483 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5908.066 | 0.9316 | 0.7112 | 0.4546 | |
| BT-483 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 5908.066 | 0.9133 | 0.6385 | 0.4546 | |
| BT-483 | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 5908.066 | 0.9165 | 0.6508 | 0.4546 | |
| BT-483 | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 5908.066 | 0.8906 | 0.5502 | 0.4546 | |
| BT-483 | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 5908.066 | 0.7472 | 0.0534 | 0.4546 |