Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10880.072 | 0.7953 | 0.7360 | 1.6177 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10880.072 | 0.2679 | -0.1140 | 1.6177 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 5904.072 | 1.0442 | 1.0863 | 1.0242 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 5904.072 | 0.9899 | 0.9803 | 1.0242 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 5904.072 | 0.9808 | 0.9625 | 1.0242 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 5904.072 | 1.0206 | 1.0401 | 1.0242 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 5904.072 | 1.0277 | 1.0540 | 1.0242 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 5904.072 | 0.9960 | 0.9922 | 1.0242 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 5904.072 | 1.0267 | 1.0521 | 1.0242 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 5904.072 | 0.8817 | 0.7686 | 1.0242 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 5904.072 | 0.4131 | -0.1564 | 1.0242 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10385.072 | 0.9800 | 0.9576 | 0.9450 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10385.072 | 0.9174 | 0.8255 | 0.9450 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10385.072 | 0.9812 | 0.9603 | 0.9450 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10385.072 | 0.9494 | 0.8931 | 0.9450 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10385.072 | 0.9539 | 0.9025 | 0.9450 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10385.072 | 0.8886 | 0.7651 | 0.9450 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10385.072 | 0.9315 | 0.8554 | 0.9450 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10385.072 | 0.9045 | 0.7985 | 0.9450 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10385.072 | 0.5485 | 0.0594 | 0.9450 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10581.072 | 0.9877 | 0.9766 | 1.0484 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10581.072 | 0.9062 | 0.8206 | 1.0484 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10581.072 | 0.9552 | 0.9144 | 1.0484 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10581.072 | 0.9637 | 0.9308 | 1.0484 | |
| BT-20 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10581.072 | 0.9991 | 0.9983 | 1.0484 |