Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7455.066 | 0.8785 | 0.8101 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7455.066 | 0.8308 | 0.7337 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7456.066 | 1.0178 | 1.0199 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7456.066 | 1.0189 | 1.0211 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7456.066 | 1.0054 | 1.0061 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7456.066 | 1.0597 | 1.0663 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7456.066 | 1.0619 | 1.0687 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7456.066 | 0.9906 | 0.9894 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7456.066 | 0.9803 | 0.9778 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7456.066 | 0.8531 | 0.8291 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7456.066 | 0.5662 | 0.4525 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7457.066 | 0.9921 | 0.9905 | 1.6601 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7457.066 | 0.8894 | 0.8637 | 1.6601 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7457.066 | 0.9224 | 0.9051 | 1.6601 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7457.066 | 0.9398 | 0.9265 | 1.6601 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7457.066 | 0.9631 | 0.9552 | 1.6601 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7457.066 | 0.9079 | 0.8870 | 1.6601 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7457.066 | 0.9196 | 0.9016 | 1.6601 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7457.066 | 0.8709 | 0.8402 | 1.6601 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7457.066 | 0.6368 | 0.5239 | 1.6601 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 10469.066 | 0.9696 | 0.9624 | 1.6299 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 10469.066 | 0.9346 | 0.9187 | 1.6299 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 10469.066 | 0.9312 | 0.9144 | 1.6299 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 10469.066 | 0.9584 | 0.9486 | 1.6299 | |
| HCC1954 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 10469.066 | 0.9887 | 0.9861 | 1.6299 |