Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7450.066 | 0.9838 | 0.9864 | 2.3863 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7450.066 | 0.9791 | 0.9824 | 2.3863 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7450.066 | 0.9550 | 0.9617 | 2.3863 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7450.066 | 0.9345 | 0.9440 | 2.3863 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7450.066 | 0.9751 | 0.9789 | 2.3863 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7450.066 | 0.9742 | 0.9782 | 2.3863 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7450.066 | 0.4988 | 0.4943 | 2.3863 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7451.066 | 1.0526 | 1.0518 | 2.0040 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7451.066 | 1.0010 | 1.0010 | 2.0040 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7451.066 | 1.0067 | 1.0067 | 2.0040 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7451.066 | 0.9831 | 0.9830 | 2.0040 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7451.066 | 1.0233 | 1.0231 | 2.0040 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7451.066 | 0.9682 | 0.9681 | 2.0040 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7451.066 | 1.0805 | 1.0788 | 2.0040 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7451.066 | 0.8741 | 0.8701 | 2.0040 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7451.066 | 0.6809 | 0.6510 | 2.0040 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7452.066 | 1.0012 | 1.0016 | 1.4723 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7452.066 | 0.9792 | 0.9716 | 1.4723 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7452.066 | 0.9779 | 0.9699 | 1.4723 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7452.066 | 0.9914 | 0.9883 | 1.4723 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7452.066 | 0.9973 | 0.9963 | 1.4723 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7452.066 | 0.9849 | 0.9794 | 1.4723 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7452.066 | 1.0001 | 1.0001 | 1.4723 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7452.066 | 0.9803 | 0.9731 | 1.4723 | |
| HCC1937 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7452.066 | 0.6873 | 0.5503 | 1.4723 |