Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7448.066 | 0.9547 | 0.9660 | 2.7001 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7448.066 | 0.9318 | 0.9483 | 2.7001 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7448.066 | 1.0175 | 1.0129 | 2.7001 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7448.066 | 0.9632 | 0.9724 | 2.7001 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7448.066 | 0.8372 | 0.8727 | 2.7001 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7449.066 | 1.0117 | 1.0119 | 1.9622 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7449.066 | 0.9995 | 0.9995 | 1.9622 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7449.066 | 0.9825 | 0.9821 | 1.9622 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7449.066 | 1.0107 | 1.0109 | 1.9622 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7449.066 | 0.9940 | 0.9938 | 1.9622 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7449.066 | 0.9704 | 0.9696 | 1.9622 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7449.066 | 1.0022 | 1.0023 | 1.9622 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7449.066 | 0.9986 | 0.9986 | 1.9622 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7449.066 | 0.9574 | 0.9561 | 1.9622 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 10442.066 | 1.0390 | 1.0469 | 1.6519 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 10442.066 | 0.9980 | 0.9975 | 1.6519 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 10442.066 | 0.9913 | 0.9894 | 1.6519 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 10442.066 | 1.0215 | 1.0259 | 1.6519 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 10442.066 | 1.0358 | 1.0431 | 1.6519 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 10442.066 | 0.9725 | 0.9665 | 1.6519 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 10442.066 | 0.9873 | 0.9846 | 1.6519 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 10442.066 | 0.9834 | 0.9798 | 1.6519 | |
| HCC1569 | HER2amp | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 10442.066 | 0.6767 | 0.5789 | 1.6519 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7450.066 | 0.9402 | 0.9490 | 2.3863 | |
| HCC1806 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7450.066 | 0.9616 | 0.9675 | 2.3863 |