Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 9830.017 | 1.0114 | 1.0122 | 1.8576 | |
| SUM149PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 9830.017 | 1.1191 | 1.1248 | 1.8576 | |
| SUM149PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 9830.017 | 0.9581 | 0.9545 | 1.8576 | |
| SUM149PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 9830.017 | 0.9187 | 0.9108 | 1.8576 | |
| SUM149PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 9830.017 | 0.6788 | 0.6234 | 1.8576 | |
| SUM149PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 9830.017 | 0.4932 | 0.3670 | 1.8576 | |
| SUM149PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 9830.017 | 0.3064 | 0.0579 | 1.8576 | |
| SUM149PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 9830.017 | 0.1367 | -0.3148 | 1.8576 | |
| SUM149PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 9830.017 | 0.0348 | -0.6719 | 1.8576 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7918.017 | 0.8896 | 0.9278 | 3.1833 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7918.017 | 0.9814 | 0.9882 | 3.1833 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7918.017 | 0.8231 | 0.8813 | 3.1833 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7918.017 | 0.7524 | 0.8290 | 3.1833 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7918.017 | 0.4097 | 0.5111 | 3.1833 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7918.017 | 0.3368 | 0.4208 | 3.1833 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7918.017 | 0.1415 | 0.0820 | 3.1833 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7918.017 | 0.2603 | 0.3103 | 3.1833 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7918.017 | 0.0901 | -0.0611 | 3.1833 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7919.017 | 1.0186 | 1.0097 | 3.7958 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7919.017 | 1.0214 | 1.0112 | 3.7958 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7919.017 | 1.0084 | 1.0044 | 3.7958 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7919.017 | 0.8198 | 0.8980 | 3.7958 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7919.017 | 0.4057 | 0.5769 | 3.7958 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7919.017 | 0.2271 | 0.3533 | 3.7958 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7919.017 | 0.1404 | 0.1923 | 3.7958 |