Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 9042.016 | 0.2517 | 0.2330 | 2.8524 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 9042.016 | 0.5370 | 0.6083 | 2.8524 | |
| SUM185PE | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7921.016 | 0.9837 | 0.9508 | 0.6622 | |
| SUM185PE | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7921.016 | 1.0295 | 1.0899 | 0.6622 | |
| SUM185PE | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7921.016 | 1.0005 | 1.0015 | 0.6622 | |
| SUM185PE | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7921.016 | 0.9807 | 0.9420 | 0.6622 | |
| SUM185PE | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7921.016 | 0.9943 | 0.9829 | 0.6622 | |
| SUM185PE | TNBC | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7921.016 | 0.9984 | 0.9952 | 0.6622 | |
| SUM185PE | TNBC | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7921.016 | 0.9442 | 0.8339 | 0.6622 | |
| SUM185PE | TNBC | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7921.016 | 0.9929 | 0.9787 | 0.6622 | |
| SUM185PE | TNBC | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7921.016 | 0.9180 | 0.7575 | 0.6622 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.000427 | uM | 7536.016 | 0.9409 | 0.8188 | 0.6413 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.00213 | uM | 7536.016 | 0.9776 | 0.9306 | 0.6413 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.0107 | uM | 7536.016 | 0.8882 | 0.6624 | 0.6413 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.0533 | uM | 7536.016 | 0.9427 | 0.8242 | 0.6413 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.267 | uM | 7536.016 | 0.9745 | 0.9210 | 0.6413 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 1.33 | uM | 7536.016 | 0.9001 | 0.6972 | 0.6413 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 6.67 | uM | 7536.016 | 0.8923 | 0.6743 | 0.6413 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 33.3 | uM | 7536.016 | 0.4620 | -0.4001 | 0.6413 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 167 | uM | 7536.016 | 0.6054 | -0.0855 | 0.6413 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.000427 | uM | 9860.019 | 0.9956 | 0.9948 | 1.6927 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.00213 | uM | 9860.019 | 0.8735 | 0.8465 | 1.6927 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.0107 | uM | 9860.019 | 0.9942 | 0.9932 | 1.6927 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.0533 | uM | 9860.019 | 0.9615 | 0.9541 | 1.6927 | |
| SUM229PE | TNBC | - | AG1478 | EGFR | ErbB | 0.267 | uM | 9860.019 | 0.9409 | 0.9292 | 1.6927 |