Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7919.017 | 0.0828 | 0.0375 | 3.7958 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7919.017 | 0.0633 | -0.0335 | 3.7958 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7920.13 | 0.9617 | 0.9823 | 4.3955 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7920.13 | 0.9995 | 0.9998 | 4.3955 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7920.13 | 0.9405 | 0.9723 | 4.3955 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7920.13 | 0.8064 | 0.9045 | 4.3955 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7920.13 | 0.5104 | 0.7162 | 4.3955 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7920.13 | 0.2427 | 0.4492 | 4.3955 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7920.13 | 0.1603 | 0.3188 | 4.3955 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7920.13 | 0.1008 | 0.1866 | 4.3955 | |
| SUM159PT | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7920.13 | 0.0850 | 0.1415 | 4.3955 | |
| SUM185PE | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7921.017 | 1.0167 | 1.0418 | 0.8018 | |
| SUM185PE | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7921.017 | 1.0000 | 1.0000 | 0.8018 | |
| SUM185PE | TNBC | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7921.017 | 1.0054 | 1.0136 | 0.8018 | |
| SUM185PE | TNBC | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7921.017 | 0.9853 | 0.9633 | 0.8018 | |
| SUM185PE | TNBC | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7921.017 | 0.9936 | 0.9840 | 0.8018 | |
| SUM185PE | TNBC | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7921.017 | 1.0748 | 1.1882 | 0.8018 | |
| SUM185PE | TNBC | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7921.017 | 0.9551 | 0.8887 | 0.8018 | |
| SUM185PE | TNBC | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7921.017 | 0.7243 | 0.3377 | 0.8018 | |
| SUM185PE | TNBC | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7921.017 | 0.5776 | 0.0087 | 0.8018 | |
| SUM229PE | TNBC | - | 5-FU | TYMS | TYMS | 0.0492 | uM | 9860.017 | 0.9515 | 0.9429 | 1.7158 | |
| SUM229PE | TNBC | - | 5-FU | TYMS | TYMS | 0.246 | uM | 9860.017 | 0.9774 | 0.9735 | 1.7158 | |
| SUM229PE | TNBC | - | 5-FU | TYMS | TYMS | 1.23 | uM | 9860.017 | 0.9476 | 0.9383 | 1.7158 | |
| SUM229PE | TNBC | - | 5-FU | TYMS | TYMS | 6.15 | uM | 9860.017 | 0.9827 | 0.9798 | 1.7158 | |
| SUM229PE | TNBC | - | 5-FU | TYMS | TYMS | 30.7 | uM | 9860.017 | 0.7450 | 0.6847 | 1.7158 |