Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.000427 | uM | 10819.151 | 0.9651 | 0.9667 | 2.1209 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.00213 | uM | 10819.151 | 1.0311 | 1.0291 | 2.1209 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0107 | uM | 10819.151 | 1.0220 | 1.0206 | 2.1209 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0533 | uM | 10819.151 | 1.0035 | 1.0033 | 2.1209 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.267 | uM | 10819.151 | 0.9110 | 0.9140 | 2.1209 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 1.33 | uM | 10819.151 | 0.6763 | 0.6632 | 2.1209 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 6.67 | uM | 10819.151 | 0.6544 | 0.6375 | 2.1209 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 33.3 | uM | 10819.151 | 0.6806 | 0.6682 | 2.1209 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.000128 | uM | 11937.157 | 0.9850 | 0.9875 | 2.4025 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.00064 | uM | 11937.157 | 0.9905 | 0.9921 | 2.4025 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0032 | uM | 11937.157 | 0.9959 | 0.9966 | 2.4025 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.016 | uM | 11937.157 | 0.9637 | 0.9695 | 2.4025 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.08 | uM | 11937.157 | 0.9939 | 0.9949 | 2.4025 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.4 | uM | 11937.157 | 0.7654 | 0.7894 | 2.4025 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 2 | uM | 11937.157 | 0.6455 | 0.6669 | 2.4025 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 10 | uM | 11937.157 | 0.5127 | 0.5145 | 2.4025 | |
| SUM149PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 50 | uM | 11937.157 | 0.5383 | 0.5455 | 2.4025 | |
| SUM159PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0000853 | uM | 10520.139 | 0.8328 | 0.9022 | 3.6491 | |
| SUM159PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.000427 | uM | 10520.139 | 0.8972 | 0.9414 | 3.6491 | |
| SUM159PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.00213 | uM | 10520.139 | 0.7976 | 0.8798 | 3.6491 | |
| SUM159PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0107 | uM | 10520.139 | 0.8877 | 0.9357 | 3.6491 | |
| SUM159PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.0533 | uM | 10520.139 | 0.8285 | 0.8995 | 3.6491 | |
| SUM159PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 0.267 | uM | 10520.139 | 0.4400 | 0.5971 | 3.6491 | |
| SUM159PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 1.33 | uM | 10520.139 | 0.1951 | 0.2780 | 3.6491 | |
| SUM159PT | TNBC | Basal B | ICRF-193 | TOP2 | TOP | 6.67 | uM | 10520.139 | 0.2009 | 0.2882 | 3.6491 |