Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.0032 | uM | 12509.157 | 1.0242 | 1.0376 | 1.2837 | |
| 184A1 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.016 | uM | 12509.157 | 0.9749 | 0.9607 | 1.2837 | |
| 184A1 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.08 | uM | 12509.157 | 0.8818 | 0.8134 | 1.2837 | |
| 184A1 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.4 | uM | 12509.157 | 0.8920 | 0.8297 | 1.2837 | |
| 184A1 | NM | Basal | ICRF-193 | TOP2 | TOP | 2 | uM | 12509.157 | 0.8285 | 0.7273 | 1.2837 | |
| 184A1 | NM | Basal | ICRF-193 | TOP2 | TOP | 10 | uM | 12509.157 | 0.8376 | 0.7421 | 1.2837 | |
| 184A1 | NM | Basal | ICRF-193 | TOP2 | TOP | 50 | uM | 12509.157 | 0.7771 | 0.6433 | 1.2837 | |
| 184B5 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.0000853 | uM | 12566.171 | 0.9712 | 0.9617 | 1.5151 | |
| 184B5 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.000427 | uM | 12566.171 | 0.9612 | 0.9484 | 1.5151 | |
| 184B5 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.00213 | uM | 12566.171 | 0.9747 | 0.9665 | 1.5151 | |
| 184B5 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.0107 | uM | 12566.171 | 0.9300 | 0.9065 | 1.5151 | |
| 184B5 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.0533 | uM | 12566.171 | 0.9569 | 0.9426 | 1.5151 | |
| 184B5 | NM | Basal | ICRF-193 | TOP2 | TOP | 0.267 | uM | 12566.171 | 0.8099 | 0.7401 | 1.5151 | |
| 184B5 | NM | Basal | ICRF-193 | TOP2 | TOP | 1.33 | uM | 12566.171 | 0.7281 | 0.6220 | 1.5151 | |
| 184B5 | NM | Basal | ICRF-193 | TOP2 | TOP | 6.67 | uM | 12566.171 | 0.7405 | 0.6403 | 1.5151 | |
| 184B5 | NM | Basal | ICRF-193 | TOP2 | TOP | 33.3 | uM | 12566.171 | 0.7461 | 0.6484 | 1.5151 | |
| 600MPE | HR+ | Luminal | ICRF-193 | TOP2 | TOP | 0.000128 | uM | 12224.157 | 0.9572 | 0.9201 | 1.0737 | |
| 600MPE | HR+ | Luminal | ICRF-193 | TOP2 | TOP | 0.00064 | uM | 12224.157 | 0.9581 | 0.9218 | 1.0737 | |
| 600MPE | HR+ | Luminal | ICRF-193 | TOP2 | TOP | 0.0032 | uM | 12224.157 | 0.9201 | 0.8507 | 1.0737 | |
| 600MPE | HR+ | Luminal | ICRF-193 | TOP2 | TOP | 0.016 | uM | 12224.157 | 0.9736 | 0.9507 | 1.0737 | |
| 600MPE | HR+ | Luminal | ICRF-193 | TOP2 | TOP | 0.08 | uM | 12224.157 | 0.9823 | 0.9669 | 1.0737 | |
| 600MPE | HR+ | Luminal | ICRF-193 | TOP2 | TOP | 0.4 | uM | 12224.157 | 0.9026 | 0.8179 | 1.0737 | |
| 600MPE | HR+ | Luminal | ICRF-193 | TOP2 | TOP | 2 | uM | 12224.157 | 0.9092 | 0.8303 | 1.0737 | |
| 600MPE | HR+ | Luminal | ICRF-193 | TOP2 | TOP | 10 | uM | 12224.157 | 0.9704 | 0.9449 | 1.0737 | |
| 600MPE | HR+ | Luminal | ICRF-193 | TOP2 | TOP | 50 | uM | 12224.157 | 0.8245 | 0.6710 | 1.0737 |