Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 10999.143 | 0.9858 | 0.9458 | 0.5216 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 10999.143 | 0.8853 | 0.5833 | 0.5216 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 10999.143 | 0.4436 | -0.5791 | 0.5216 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 10999.143 | 0.1495 | -0.9477 | 0.5216 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 10999.143 | 0.2177 | -0.8925 | 0.5216 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12379.143 | 1.0125 | 1.0561 | 0.4493 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12379.143 | 1.0270 | 1.1221 | 0.4493 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 12379.143 | 0.9606 | 0.8290 | 0.4493 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 12379.143 | 0.9849 | 0.9336 | 0.4493 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 12379.143 | 0.9997 | 0.9989 | 0.4493 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 12379.143 | 0.9462 | 0.7682 | 0.4493 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 12379.143 | 0.6074 | -0.3407 | 0.4493 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 12379.143 | 0.1986 | -0.9452 | 0.4493 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 12379.143 | 0.2748 | -0.8872 | 0.4493 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10938.143 | 0.9332 | 0.8685 | 1.0173 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10938.143 | 0.8090 | 0.6237 | 1.0173 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10938.143 | 0.9577 | 0.9168 | 1.0173 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10938.143 | 0.9783 | 0.9573 | 1.0173 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10938.143 | 0.9480 | 0.8977 | 1.0173 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10938.143 | 0.9651 | 0.9313 | 1.0173 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10938.143 | 0.6748 | 0.3586 | 1.0173 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10938.143 | 0.2015 | -0.5859 | 1.0173 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10938.143 | 0.0576 | -0.8792 | 1.0173 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12333.143 | 0.9748 | 0.9203 | 0.6265 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12333.143 | 0.9984 | 0.9947 | 0.6265 |