Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10818.143 | 0.7160 | 0.1732 | 0.6263 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10818.143 | 0.2854 | -0.7300 | 0.6263 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10818.143 | 0.2204 | -0.8212 | 0.6263 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12126.143 | 0.9456 | 0.8404 | 0.6729 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12126.143 | 0.9108 | 0.7406 | 0.6729 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 12126.143 | 0.9560 | 0.8706 | 0.6729 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 12126.143 | 0.9170 | 0.7584 | 0.6729 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 12126.143 | 0.9842 | 0.9532 | 0.6729 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 12126.143 | 0.9423 | 0.8310 | 0.6729 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 12126.143 | 0.9026 | 0.7176 | 0.6729 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 12126.143 | 0.3702 | -0.5432 | 0.6729 | ||
| MDA-MB-175-VII | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 12126.143 | 0.1760 | -0.8487 | 0.6729 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10643.143 | 0.9941 | 0.9760 | 0.4866 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10643.143 | 0.9413 | 0.7662 | 0.4866 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 10643.143 | 1.0145 | 1.0599 | 0.4866 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 10643.143 | 0.9494 | 0.7976 | 0.4866 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 10643.143 | 0.9726 | 0.8890 | 0.4866 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 10643.143 | 0.7710 | 0.1719 | 0.4866 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 10643.143 | 0.4712 | -0.5738 | 0.4866 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 10643.143 | 0.1572 | -0.9554 | 0.4866 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 10643.143 | 0.1931 | -0.9319 | 0.4866 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10999.143 | 1.0202 | 1.0783 | 0.5216 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10999.143 | 1.0129 | 1.0498 | 0.5216 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 10999.143 | 1.0744 | 1.2951 | 0.5216 | ||
| MDA-MB-361 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 10999.143 | 1.0298 | 1.1160 | 0.5216 |