Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10693.143 | 0.4665 | -0.2755 | 0.7509 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 11936.143 | 1.0027 | 1.0068 | 0.7979 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 11936.143 | 0.9738 | 0.9345 | 0.7979 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 11936.143 | 1.0058 | 1.0145 | 0.7979 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 11936.143 | 1.0062 | 1.0156 | 0.7979 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 11936.143 | 0.9364 | 0.8418 | 0.7979 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 11936.143 | 0.9915 | 0.9787 | 0.7979 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 11936.143 | 0.8579 | 0.6504 | 0.7979 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 11936.143 | 0.6183 | 0.0949 | 0.7979 | ||
| HCC1428 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 11936.143 | 0.4409 | -0.2835 | 0.7979 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 0.00384 | uM | 10872.143 | 0.9782 | 0.9732 | 1.6364 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 0.0192 | uM | 10872.143 | 0.9295 | 0.9126 | 1.6364 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 0.096 | uM | 10872.143 | 1.0297 | 1.0361 | 1.6364 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 0.48 | uM | 10872.143 | 1.0117 | 1.0142 | 1.6364 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 2.4 | uM | 10872.143 | 0.9724 | 0.9661 | 1.6364 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 12 | uM | 10872.143 | 0.9563 | 0.9461 | 1.6364 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 60 | uM | 10872.143 | 0.7164 | 0.6312 | 1.6364 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 300 | uM | 10872.143 | 0.3177 | -0.0076 | 1.6364 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 1500 | uM | 10872.143 | 0.2784 | -0.0844 | 1.6364 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 0.00384 | uM | 12523.143 | 0.9865 | 0.9723 | 0.9700 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 0.0192 | uM | 12523.143 | 0.9721 | 0.9426 | 0.9700 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 0.096 | uM | 12523.143 | 1.0157 | 1.0323 | 0.9700 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 0.48 | uM | 12523.143 | 0.9746 | 0.9477 | 0.9700 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 2.4 | uM | 12523.143 | 1.0131 | 1.0271 | 0.9700 | ||
| HCC1569 | HER2amp | Basal A | Ibandronate | FDPS | 12 | uM | 12523.143 | 0.9709 | 0.9400 | 0.9700 |