Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 12333.143 | 0.9521 | 0.8494 | 0.6265 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 12333.143 | 0.9404 | 0.8132 | 0.6265 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 12333.143 | 0.9068 | 0.7107 | 0.6265 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 12333.143 | 1.0285 | 1.0919 | 0.6265 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 12333.143 | 0.7067 | 0.1493 | 0.6265 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 12333.143 | 0.5267 | -0.2811 | 0.6265 | ||
| MDA-MB-415 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 12333.143 | 0.4430 | -0.4546 | 0.6265 | ||
| MDA-MB-453 | TNBC | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12414.143 | 0.9598 | 0.9323 | 1.1898 | ||
| MDA-MB-453 | TNBC | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12414.143 | 0.9178 | 0.8608 | 1.1898 | ||
| MDA-MB-453 | TNBC | Luminal | Ibandronate | FDPS | 0.096 | uM | 12414.143 | 0.9642 | 0.9396 | 1.1898 | ||
| MDA-MB-453 | TNBC | Luminal | Ibandronate | FDPS | 0.48 | uM | 12414.143 | 1.0083 | 1.0139 | 1.1898 | ||
| MDA-MB-453 | TNBC | Luminal | Ibandronate | FDPS | 2.4 | uM | 12414.143 | 0.9587 | 0.9303 | 1.1898 | ||
| MDA-MB-453 | TNBC | Luminal | Ibandronate | FDPS | 12 | uM | 12414.143 | 0.9767 | 0.9607 | 1.1898 | ||
| MDA-MB-453 | TNBC | Luminal | Ibandronate | FDPS | 60 | uM | 12414.143 | 0.8735 | 0.7851 | 1.1898 | ||
| MDA-MB-453 | TNBC | Luminal | Ibandronate | FDPS | 300 | uM | 12414.143 | 0.1797 | -0.5273 | 1.1898 | ||
| MDA-MB-453 | TNBC | Luminal | Ibandronate | FDPS | 1500 | uM | 12414.143 | 0.0715 | -0.7821 | 1.1898 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.00384 | uM | 10644.143 | 0.9824 | 0.9437 | 0.6221 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.0192 | uM | 10644.143 | 0.8712 | 0.6025 | 0.6221 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.096 | uM | 10644.143 | 0.9907 | 0.9703 | 0.6221 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.48 | uM | 10644.143 | 0.8918 | 0.6638 | 0.6221 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 2.4 | uM | 10644.143 | 0.9522 | 0.8485 | 0.6221 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 12 | uM | 10644.143 | 0.8982 | 0.6829 | 0.6221 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 60 | uM | 10644.143 | 0.9428 | 0.8192 | 0.6221 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 300 | uM | 10644.143 | 0.5979 | -0.1251 | 0.6221 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 1500 | uM | 10644.143 | 0.4258 | -0.4930 | 0.6221 |