Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.00384 | uM | 10874.143 | 0.9730 | 0.9296 | 0.7639 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.0192 | uM | 10874.143 | 1.0034 | 1.0089 | 0.7639 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.096 | uM | 10874.143 | 1.0377 | 1.0994 | 0.7639 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.48 | uM | 10874.143 | 1.0205 | 1.0539 | 0.7639 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 2.4 | uM | 10874.143 | 1.0393 | 1.1034 | 0.7639 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 12 | uM | 10874.143 | 1.0370 | 1.0973 | 0.7639 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 60 | uM | 10874.143 | 0.9098 | 0.7671 | 0.7639 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 300 | uM | 10874.143 | 0.5851 | -0.0084 | 0.7639 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 1500 | uM | 10874.143 | 0.5459 | -0.0944 | 0.7639 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.00384 | uM | 12220.143 | 0.9102 | 0.6251 | 0.4532 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.0192 | uM | 12220.143 | 0.8343 | 0.3409 | 0.4532 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.096 | uM | 12220.143 | 0.9459 | 0.7691 | 0.4532 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 0.48 | uM | 12220.143 | 1.0065 | 1.0287 | 0.4532 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 2.4 | uM | 12220.143 | 1.0295 | 1.1327 | 0.4532 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 12 | uM | 12220.143 | 0.9549 | 0.8064 | 0.4532 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 60 | uM | 12220.143 | 0.8106 | 0.2582 | 0.4532 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 300 | uM | 12220.143 | 0.8064 | 0.2438 | 0.4532 | ||
| MX1 | Unknown | Unknown | Ibandronate | FDPS | 1500 | uM | 12220.143 | 0.5152 | -0.5371 | 0.4532 | ||
| SK-BR-3 | HER2amp | Luminal | Ibandronate | FDPS | 0.00384 | uM | 11851.143 | 0.9455 | 0.9239 | 1.4447 | ||
| SK-BR-3 | HER2amp | Luminal | Ibandronate | FDPS | 0.0192 | uM | 11851.143 | 0.9993 | 0.9990 | 1.4447 | ||
| SK-BR-3 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 11851.143 | 0.9317 | 0.9044 | 1.4447 | ||
| SK-BR-3 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 11851.143 | 0.9363 | 0.9109 | 1.4447 | ||
| SK-BR-3 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 11851.143 | 0.9577 | 0.9410 | 1.4447 | ||
| SK-BR-3 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 11851.143 | 0.8606 | 0.8027 | 1.4447 | ||
| SK-BR-3 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 11851.143 | 0.7506 | 0.6398 | 1.4447 |