Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 11851.143 | 0.5259 | 0.2818 | 1.4447 | ||
| SK-BR-3 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 11851.143 | 0.4786 | 0.2009 | 1.4447 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 10875.143 | 0.9787 | 0.9484 | 0.8219 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 10875.143 | 1.0112 | 1.0273 | 0.8219 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 10875.143 | 0.9868 | 0.9679 | 0.8219 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 10875.143 | 1.0516 | 1.1261 | 0.8219 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 10875.143 | 0.9612 | 0.9061 | 0.8219 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 10875.143 | 1.0046 | 1.0112 | 0.8219 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 10875.143 | 0.5742 | 0.0184 | 0.8219 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 10875.143 | 0.4544 | -0.2340 | 0.8219 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 10875.143 | 0.3683 | -0.4067 | 0.8219 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 12428.143 | 0.9907 | 0.9738 | 0.7057 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 12428.143 | 1.0192 | 1.0548 | 0.7057 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 12428.143 | 1.0570 | 1.1633 | 0.7057 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 12428.143 | 1.0738 | 1.2123 | 0.7057 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 12428.143 | 1.0517 | 1.1481 | 0.7057 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 12428.143 | 1.0632 | 1.1813 | 0.7057 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 12428.143 | 0.6347 | 0.0503 | 0.7057 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 12428.143 | 0.5327 | -0.1806 | 0.7057 | ||
| SUM1315MO2 | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 12428.143 | 0.3970 | -0.4598 | 0.7057 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 10819.143 | 0.9801 | 0.9823 | 2.2570 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 10819.143 | 0.9057 | 0.9141 | 2.2570 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 10819.143 | 0.9643 | 0.9681 | 2.2570 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 10819.143 | 0.8843 | 0.8939 | 2.2570 | ||
| SUM149PT | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 10819.143 | 0.9619 | 0.9659 | 2.2570 |