Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 11850.143 | 0.9689 | 0.9702 | 2.1044 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 11850.143 | 0.9157 | 0.9180 | 2.1044 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 11850.143 | 0.9543 | 0.9560 | 2.1044 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 11850.143 | 1.0479 | 1.0449 | 2.1044 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 11850.143 | 0.9627 | 0.9642 | 2.1044 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 11850.143 | 1.0065 | 1.0061 | 2.1044 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 11850.143 | 0.5253 | 0.4729 | 2.1044 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 11850.143 | 0.0902 | -0.3623 | 2.1044 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 11850.143 | 0.0645 | -0.4564 | 2.1044 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 10873.143 | 0.9901 | 0.9845 | 1.2785 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 10873.143 | 0.9830 | 0.9734 | 1.2785 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 10873.143 | 0.9964 | 0.9944 | 1.2785 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 10873.143 | 0.9620 | 0.9403 | 1.2785 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 10873.143 | 0.9749 | 0.9607 | 1.2785 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 10873.143 | 0.9145 | 0.8649 | 1.2785 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 10873.143 | 0.7001 | 0.5132 | 1.2785 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 10873.143 | 0.4233 | 0.0209 | 1.2785 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 10873.143 | 0.4168 | 0.0087 | 1.2785 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 12400.143 | 0.9503 | 0.9231 | 1.3002 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 12400.143 | 0.9081 | 0.8570 | 1.3002 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 12400.143 | 0.9598 | 0.9379 | 1.3002 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 12400.143 | 1.0626 | 1.0956 | 1.3002 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 12400.143 | 0.9423 | 0.9106 | 1.3002 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 12400.143 | 1.0083 | 1.0128 | 1.3002 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 12400.143 | 0.8233 | 0.7223 | 1.3002 |