Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 12400.143 | 0.4475 | 0.0776 | 1.3002 | ||
| HCC70 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 12400.143 | 0.4423 | 0.0680 | 1.3002 | ||
| Hs 578T | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 10694.143 | 0.9927 | 0.9934 | 2.2259 | ||
| Hs 578T | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 10694.143 | 0.9583 | 0.9621 | 2.2259 | ||
| Hs 578T | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 10694.143 | 0.9305 | 0.9363 | 2.2259 | ||
| Hs 578T | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 10694.143 | 0.9047 | 0.9120 | 2.2259 | ||
| Hs 578T | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 10694.143 | 0.9619 | 0.9654 | 2.2259 | ||
| Hs 578T | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 10694.143 | 0.4405 | 0.3837 | 2.2259 | ||
| Hs 578T | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 10694.143 | 0.2468 | 0.0667 | 2.2259 | ||
| Hs 578T | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 10694.143 | 0.0598 | -0.4357 | 2.2259 | ||
| Hs 578T | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 10694.143 | 0.0134 | -0.7121 | 2.2259 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10816.143 | 1.2290 | 2.0273 | 0.4975 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10816.143 | 1.1093 | 1.4635 | 0.4975 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 10816.143 | 1.0638 | 1.2646 | 0.4975 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 10816.143 | 1.0898 | 1.3773 | 0.4975 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 10816.143 | 1.2265 | 2.0145 | 0.4975 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 12 | uM | 10816.143 | 1.2473 | 2.1184 | 0.4975 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 60 | uM | 10816.143 | 1.1823 | 1.8005 | 0.4975 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 300 | uM | 10816.143 | 0.3691 | -0.7303 | 0.4975 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 1500 | uM | 10816.143 | 0.3865 | -0.7041 | 0.4975 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12319.143 | 0.9393 | 0.7721 | 0.5178 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12319.143 | 0.8913 | 0.6013 | 0.5178 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 0.096 | uM | 12319.143 | 1.0807 | 1.3234 | 0.5178 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 0.48 | uM | 12319.143 | 0.8147 | 0.3463 | 0.5178 | ||
| LY2 | HR+ | Luminal | Ibandronate | FDPS | 2.4 | uM | 12319.143 | 0.9959 | 0.9841 | 0.5178 |