Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 10577.143 | 1.0079 | 1.0162 | 0.9750 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 10577.143 | 0.9649 | 0.9281 | 0.9750 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 10577.143 | 0.9989 | 0.9978 | 0.9750 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 10577.143 | 0.9651 | 0.9283 | 0.9750 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 10577.143 | 0.8414 | 0.6753 | 0.9750 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 10577.143 | 0.5383 | 0.0595 | 0.9750 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 10577.143 | 0.4796 | -0.0588 | 0.9750 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 10937.143 | 0.9854 | 0.9777 | 1.3133 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 10937.143 | 0.9537 | 0.9290 | 1.3133 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 10937.143 | 1.0314 | 1.0477 | 1.3133 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 10937.143 | 1.0600 | 1.0907 | 1.3133 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 10937.143 | 1.0011 | 1.0017 | 1.3133 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 10937.143 | 1.0014 | 1.0021 | 1.3133 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 10937.143 | 0.7434 | 0.5957 | 1.3133 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 10937.143 | 0.4201 | 0.0333 | 1.3133 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 10937.143 | 0.3459 | -0.1089 | 1.3133 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 0.00384 | uM | 10578.143 | 0.9855 | 0.9828 | 1.6935 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 0.0192 | uM | 10578.143 | 0.9137 | 0.8962 | 1.6935 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 0.096 | uM | 10578.143 | 0.9865 | 0.9841 | 1.6935 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 0.48 | uM | 10578.143 | 0.9634 | 0.9564 | 1.6935 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 2.4 | uM | 10578.143 | 0.9478 | 0.9376 | 1.6935 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 12 | uM | 10578.143 | 0.8653 | 0.8362 | 1.6935 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 60 | uM | 10578.143 | 0.5696 | 0.4344 | 1.6935 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 300 | uM | 10578.143 | 0.1427 | -0.3666 | 1.6935 | ||
| HCC38 | TNBC | Basal B | Ibandronate | FDPS | 1500 | uM | 10578.143 | 0.0876 | -0.5253 | 1.6935 |