Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Ibandronate | FDPS | 0.096 | uM | 10880.143 | 1.0387 | 1.0478 | 1.6077 | ||
| AU565 | HER2amp | Luminal | Ibandronate | FDPS | 0.48 | uM | 10880.143 | 1.0445 | 1.0550 | 1.6077 | ||
| AU565 | HER2amp | Luminal | Ibandronate | FDPS | 2.4 | uM | 10880.143 | 0.9905 | 0.9882 | 1.6077 | ||
| AU565 | HER2amp | Luminal | Ibandronate | FDPS | 12 | uM | 10880.143 | 1.0321 | 1.0397 | 1.6077 | ||
| AU565 | HER2amp | Luminal | Ibandronate | FDPS | 60 | uM | 10880.143 | 0.8486 | 0.8058 | 1.6077 | ||
| AU565 | HER2amp | Luminal | Ibandronate | FDPS | 300 | uM | 10880.143 | 0.5575 | 0.3905 | 1.6077 | ||
| AU565 | HER2amp | Luminal | Ibandronate | FDPS | 1500 | uM | 10880.143 | 0.4419 | 0.2035 | 1.6077 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 10581.143 | 0.9859 | 0.9688 | 0.9062 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 10581.143 | 0.7723 | 0.5038 | 0.9062 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 10581.143 | 1.0123 | 1.0271 | 0.9062 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 10581.143 | 0.8786 | 0.7338 | 0.9062 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 10581.143 | 0.9666 | 0.9263 | 0.9062 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 10581.143 | 0.8037 | 0.5715 | 0.9062 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 10581.143 | 0.5786 | 0.0935 | 0.9062 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 10581.143 | 0.2985 | -0.4733 | 0.9062 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 10581.143 | 0.0661 | -0.9002 | 0.9062 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 11854.143 | 1.0387 | 1.0691 | 1.1185 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 11854.143 | 1.0130 | 1.0232 | 1.1185 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 0.096 | uM | 11854.143 | 1.0002 | 1.0004 | 1.1185 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 0.48 | uM | 11854.143 | 1.0323 | 1.0576 | 1.1185 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 2.4 | uM | 11854.143 | 1.0113 | 1.0201 | 1.1185 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 12 | uM | 11854.143 | 0.8470 | 0.7241 | 1.1185 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 60 | uM | 11854.143 | 0.4726 | 0.0232 | 1.1185 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 300 | uM | 11854.143 | 0.2604 | -0.3994 | 1.1185 | ||
| BT-20 | TNBC | Basal A | Ibandronate | FDPS | 1500 | uM | 11854.143 | 0.0863 | -0.7762 | 1.1185 |