Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7486.092 | 0.9907 | 0.9834 | 1.1266 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7486.092 | 1.0392 | 1.0695 | 1.1266 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7486.092 | 1.0119 | 1.0210 | 1.1266 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7486.092 | 1.0690 | 1.1220 | 1.1266 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7486.092 | 0.9829 | 0.9696 | 1.1266 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7486.092 | 0.8331 | 0.7007 | 1.1266 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7486.092 | 0.4858 | 0.0538 | 1.1266 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7486.092 | 0.0452 | -0.8719 | 1.1266 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7486.092 | 0.0005 | -0.9978 | 1.1266 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7487.09 | 1.0091 | 1.0119 | 1.5226 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7487.09 | 1.0776 | 1.1006 | 1.5226 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7487.09 | 1.0150 | 1.0196 | 1.5226 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7487.09 | 1.0550 | 1.0715 | 1.5226 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7487.09 | 1.0702 | 1.0911 | 1.5226 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7487.09 | 1.0208 | 1.0273 | 1.5226 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7487.09 | 0.9148 | 0.8863 | 1.5226 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 113 | uM | 7487.09 | 0.0335 | -0.7850 | 1.5226 | |
| MCF 10F | NM | - | Imatinib | ABL/KIT/PDGFR | nRTK | 565 | uM | 7487.09 | 0.0004 | -0.9891 | 1.5226 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00145 | uM | 7489.09 | 0.9874 | 0.9872 | 1.9790 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.00723 | uM | 7489.09 | 1.1107 | 1.1089 | 1.9790 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.0362 | uM | 7489.09 | 1.0038 | 1.0038 | 1.9790 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.181 | uM | 7489.09 | 1.0860 | 1.0851 | 1.9790 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 0.904 | uM | 7489.09 | 1.0532 | 1.0531 | 1.9790 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 4.52 | uM | 7489.09 | 1.0149 | 1.0150 | 1.9790 | |
| MCF12A | NM | Basal B | Imatinib | ABL/KIT/PDGFR | nRTK | 22.6 | uM | 7489.09 | 0.8010 | 0.7879 | 1.9790 |