Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Ibandronate | FDPS | 2.4 | uM | 11055.143 | 1.0108 | 1.0125 | 1.7215 | ||
| HCC1954 | HER2amp | Basal A | Ibandronate | FDPS | 12 | uM | 11055.143 | 1.0203 | 1.0234 | 1.7215 | ||
| HCC1954 | HER2amp | Basal A | Ibandronate | FDPS | 60 | uM | 11055.143 | 0.5926 | 0.4758 | 1.7215 | ||
| HCC1954 | HER2amp | Basal A | Ibandronate | FDPS | 300 | uM | 11055.143 | 0.2976 | -0.0108 | 1.7215 | ||
| HCC1954 | HER2amp | Basal A | Ibandronate | FDPS | 1500 | uM | 11055.143 | 0.2696 | -0.0661 | 1.7215 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 0.00384 | uM | 10996.143 | 1.0161 | 1.1084 | 0.3034 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 0.0192 | uM | 10996.143 | 1.0204 | 1.1376 | 0.3034 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 0.096 | uM | 10996.143 | 1.0074 | 1.0495 | 0.3034 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 0.48 | uM | 10996.143 | 0.9914 | 0.9437 | 0.3034 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 2.4 | uM | 10996.143 | 0.9754 | 0.8426 | 0.3034 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 12 | uM | 10996.143 | 0.8247 | 0.0596 | 0.3034 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 60 | uM | 10996.143 | 0.6571 | -0.4988 | 0.3034 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 300 | uM | 10996.143 | 0.4931 | -0.8055 | 0.3034 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 1500 | uM | 10996.143 | 0.4821 | -0.8193 | 0.3034 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 0.00384 | uM | 12192.143 | 0.9111 | 0.7122 | 0.5995 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 0.0192 | uM | 12192.143 | 0.9826 | 0.9423 | 0.5995 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 0.096 | uM | 12192.143 | 1.0802 | 1.2747 | 0.5995 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 0.48 | uM | 12192.143 | 1.1281 | 1.4455 | 0.5995 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 2.4 | uM | 12192.143 | 1.0602 | 1.2049 | 0.5995 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 12 | uM | 12192.143 | 0.9260 | 0.7594 | 0.5995 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 60 | uM | 12192.143 | 0.5830 | -0.1868 | 0.5995 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 300 | uM | 12192.143 | 0.4333 | -0.5043 | 0.5995 | ||
| HCC2185 | TNBC | Luminal | Ibandronate | FDPS | 1500 | uM | 12192.143 | 0.3854 | -0.5923 | 0.5995 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 0.00384 | uM | 10577.143 | 1.0303 | 1.0623 | 0.9750 | ||
| HCC3153 | TNBC | Basal A | Ibandronate | FDPS | 0.0192 | uM | 10577.143 | 0.9355 | 0.8678 | 0.9750 |