Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 5895.067 | 1.0688 | 1.0970 | 1.4053 | |
| 184A1 | NM | Basal | Ispinesib | KSP | Kinesin | 0.000427 | uM | 5895.067 | 1.0227 | 1.0322 | 1.4053 | |
| 184A1 | NM | Basal | Ispinesib | KSP | Kinesin | 0.00213 | uM | 5895.067 | 1.0318 | 1.0451 | 1.4053 | |
| 184A1 | NM | Basal | Ispinesib | KSP | Kinesin | 0.0107 | uM | 5895.067 | 1.0381 | 1.0539 | 1.4053 | |
| 184A1 | NM | Basal | Ispinesib | KSP | Kinesin | 0.0533 | uM | 5895.067 | 0.8338 | 0.7574 | 1.4053 | |
| 184A1 | NM | Basal | Ispinesib | KSP | Kinesin | 0.267 | uM | 5895.067 | 0.8266 | 0.7466 | 1.4053 | |
| 184A1 | NM | Basal | Ispinesib | KSP | Kinesin | 1.33 | uM | 5895.067 | 0.8618 | 0.7992 | 1.4053 | |
| 184A1 | NM | Basal | Ispinesib | KSP | Kinesin | 6.67 | uM | 5895.067 | 0.2291 | -0.2991 | 1.4053 | |
| 184A1 | NM | Basal | Ispinesib | KSP | Kinesin | 33.3 | uM | 5895.067 | 0.0130 | -0.9091 | 1.4053 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 5896.067 | 1.0161 | 1.0221 | 1.4536 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.000427 | uM | 5896.067 | 1.0152 | 1.0208 | 1.4536 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.00213 | uM | 5896.067 | 0.9906 | 0.9871 | 1.4536 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.0107 | uM | 5896.067 | 0.9326 | 0.9062 | 1.4536 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.0533 | uM | 5896.067 | 0.7088 | 0.5783 | 1.4536 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.267 | uM | 5896.067 | 0.6411 | 0.4729 | 1.4536 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 1.33 | uM | 5896.067 | 0.6819 | 0.5368 | 1.4536 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 6.67 | uM | 5896.067 | 0.3301 | -0.0670 | 1.4536 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 33.3 | uM | 5896.067 | 0.0069 | -0.9349 | 1.4536 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.0000853 | uM | 5897.067 | 1.0439 | 1.0734 | 1.1908 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.000427 | uM | 5897.067 | 1.0115 | 1.0194 | 1.1908 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.00213 | uM | 5897.067 | 1.0301 | 1.0505 | 1.1908 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.0107 | uM | 5897.067 | 1.0329 | 1.0551 | 1.1908 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.0533 | uM | 5897.067 | 0.9142 | 0.8548 | 1.1908 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 0.267 | uM | 5897.067 | 0.8502 | 0.7453 | 1.1908 | |
| 184B5 | NM | Basal | Ispinesib | KSP | Kinesin | 1.33 | uM | 5897.067 | 0.8901 | 0.8137 | 1.1908 |