Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9453.001 | 0.9736 | 0.9580 | 1.2616 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9453.001 | 0.9874 | 0.9799 | 1.2616 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9453.001 | 0.3972 | -0.0380 | 1.2616 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 9453.001 | 0.3132 | -0.2031 | 1.2616 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 9453.001 | 0.3214 | -0.1866 | 1.2616 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 9453.001 | 0.3180 | -0.1934 | 1.2616 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 33.3 | uM | 9453.001 | 0.2415 | -0.3514 | 1.2616 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9469.001 | 1.0456 | 1.0893 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9469.001 | 0.9949 | 0.9900 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9469.001 | 1.0286 | 1.0560 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9469.001 | 1.0334 | 1.0655 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9469.001 | 0.3293 | -0.3267 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 9469.001 | 0.3464 | -0.2925 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 9469.001 | 0.3853 | -0.2147 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 9469.001 | 0.3322 | -0.3210 | 1.0202 | |
| HCC38 | TNBC | Basal B | GSK461364 | PLK1 | PLK | 33.3 | uM | 9469.001 | 0.0969 | -0.7970 | 1.0202 | |
| HCC70 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7856.001 | 1.0309 | 1.0876 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7856.001 | 1.1632 | 1.4736 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7856.001 | 1.0025 | 1.0069 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7856.001 | 0.4774 | -0.2929 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7856.001 | 0.4423 | -0.3650 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 0.267 | uM | 7856.001 | 0.4890 | -0.2687 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 1.33 | uM | 7856.001 | 0.6830 | 0.1700 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 6.67 | uM | 7856.001 | 0.5441 | -0.1503 | 0.7111 | |
| HCC70 | TNBC | Basal A | GSK461364 | PLK1 | PLK | 33.3 | uM | 7856.001 | 0.3983 | -0.4520 | 0.7111 |